Topic outline

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  Advanced Molecular Biology 2018-2019

  
  

  • Announcements Forum
  • Course Forum
  • EXAM rules Page
  • Exam: starting question list, oral interview. Page
  • About internal activities Page
  • REMINDER

    Materials contained in these webpages are protected by copyright and should not be copied, printed or distributed outside the groups participating in this specific activity. 

  • Campusnet URL
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  Student activities

  wikis, databases, background, methodology, Forum

  • Internal Activities - adjourned May 20 File
  • Reports 2019 - Grades File
  • AMB 2018-2019 - General Table File
  • Student Wiki on methodology
  • REPORT CALENDAR, adjourned 26/4 Wiki
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  Introduction to Regulatory Genomics

  This section concerns a general introduction to the subjects of this course. Assessment of Students' background in this specific subject is planned. 

  • Textbook G Folder
  • Activity 1 - Ex. Levine - Open version Quiz
  • Lesson 0 (intro) Folder
  • audio Folder
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  Chapter 1 - Genomes, Epigenomes and Nuclear organization

  i progetti funzionali

  • Ch.1 PDF Folder
  • Audio-1 Folder
  • Textbook_1 Folder
  • Research Paper_1 Folder
  • A guide for studying Research Paper 1 File
  • Activity 2 - Elements in Human Genome - open version Quiz
  • Activity 3 - A database of proteins associated to the nuclear lamina
  • Activity 4 - Reddy et al. - open version Quiz
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  Chapter 2 - Establishment & maintenance of chromatin features

  • Ch. 2 pdf Folder
  • Audio-2 Folder
  • Textbook_2 Folder
  • Research_paper_2 Folder
  • On Research Paper 2 Wiki
  • Bibliography_2 Folder
  • Activity 5 - Few basic questions before proceeding - open version Lesson
  • Activity 6 - An additional model of heterochromatin establishment and maintenance - open version Lesson
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  Chapter 3 - Transcriptional Regulation

  • Ch. 3 pdf Folder
  • Lesson 3.5 - recordings, webex, pdfs. Folder
  • Audio 3 Folder
  • Textbooks - 3 Folder
  • Research Paper_3 Folder
  • Research Paper 3 - Discussion, questions and answers Wiki
  • Bibliography Folder
  • Activity 7 - Promoters - open version Lesson
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  Chapter 4 - Transcriptomes and post-transcriptional regulation

  What transcriptomes across different cell lines and tissues tell us. GO studies. Alternative transcripts and alternative splicing control. Small RNAs and RNA interference. Long-noncoding RNAs, miRNAs and Regulatory networks.

   

  • Ch.4 pdf Folder
  • audio_4 Folder
  • Textbook - 4 Folder
  • Research Paper_4 Folder

    How HITS-CLIP can be modified for the accurate analysis of miRNA-mRNA pairs

  • Research Paper 4 - Discussion Wiki
  • Activity 8: Lesson 4.4 tail - further details on RNA stability and localization
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  Chapter 5 - Applications in Medicine

  Prof. CUTRUPI lessons & activities 

  • Lesson pdf- 6 Folder
  • Research Papers - 6 Folder
  • Textbook - 6 Folder
  • Bibliography - 6 Folder
  • Lesson 1- Training Quiz
  • Lesson4- Training Quiz
  • Lesson 6- Training Quiz
  • Lesson 7- Training Quiz
  • Lnc13inCeliacDisease- Training Quiz
  • Lesson 3- Training Quiz
  • Progeria- Training Quiz
  • Progeria Therapy Quiz
  • Lesson10-Training Quiz
  • SingleCell-Training Quiz
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  Practice

  • Basic Concepts- Overview File
  • Bioinformatics Practice- First Part- Primary and secondary databases File
  • Bioinformatics Practice- Second Part-Gene regulation File
  • GeneList File
  • Bioinformatics Report Assignment
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  Auxiliaries

  • BACKGROUND: Human Genome Project + other basic tutorials Book
  • BACKGROUND: NGS sequencing technologies Book
  • BACKGROUND: DNA microarrays Book
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  EXAM TESTS