Ch 3 - Lessons streaming

1. Ch 3 - Transcriptional regulation

Chapter 3, Lesson 1 is composed of 3 parts.

PART 1:

PART 2:

PART 2:

2. Combinatorial role of Transcription factors at Enhancers

Introductory Part 1 by MDB is composed of 2 pieces:

Lesson 2, Part 1 .1 

Lesson 2, Part 1.2 

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Part 2 is composed of three videos by important scientists, followed by comments by your Prof. (two additional parts 2.2.1 and 2.2.2). 

VIDEO on early stages development in insects, by Eric Wieschaus (Nobel Prize  in Physiology or Medicine 1995):

<iframe width="560" height="315" src="https://www.youtube.com/embed/Ncxs21KEj0g" frameborder="0" allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe>

How Transcription facors work combinatorially in enhancers: VIDEO by Michael Levine 

<iframe width="560" height="315" src="https://www.youtube.com/embed/Cfgze3BItDY" frameborder="0" allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe>

Why most genes are controlled by more than one enhancer: precision. by Michael Levine

<iframe width="560" height="315" src="https://www.youtube.com/embed/FLa3oRPxNLM" frameborder="0" allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe>

Lesson 2.2 (two parts): commentary 

3. How TF/Enhancers work

Chapter 3, Lesson 3 is composed of three videos.

PART 1

PART 2.1

PART 2.2  

This is the movie shown in Part 1, Slide 8:

This movie is taken from Swinstead et al., 2016, Cell 165, 1–13, April 21, 2016 

http://dx.doi.org/10.1016/j.cell.2016.02.067 

4. Enhancer programming and activation

Lesson 4 starts with a Conference video by Dr. Christopher Glass (Co-Author of the TextBook Review by Heinz 2015)

<iframe width="560" height="315" src="https://www.youtube.com/embed/T5O6RQN_bDo" frameborder="0" allow="accelerometer; autoplay; encrypted-media; gyroscope; picture-in-picture" allowfullscreen></iframe>

This subject is discussed in the following:

PART 1:

PART 2:

PART 3: 

5. Lesson 5 - Promoters

This Lesson refers to your TextBook Review by Haberle & Lenhard (2016). 

PART 1:

PART 2:

PART 3: